Selectin E/CD62e Antikörper

Produktnummer ABIN6569172

Dieser Anti-Selectin E/CD62e Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Selectin E/CD62e in WB, IHC und IF. Geeignet für Human und Maus.

Kurzübersicht für Selectin E/CD62e Antikörper (ABIN6569172)

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Selectin E/CD62e Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Selectin E/CD62e Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human SELE

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Selectin E/CD62e

Target: Selectin E/CD62e (SELE) (Selectin E (SELE))

Andere Bezeichnung: E-Selectin

Hintergrund:

Synonyms: CD26E,CD62 antigen-like family member E,CD62E,E selectin,E-selectin,ELAM,ELAM-1,ELAM1,Endothelial adhesion molecule 1,Endothelial leukocyte adhesion molecule 1,ESEL,LECAM2,Leukocyte-endothelial cell adhesion molecule 2,LYAM2,Sele,Selectin E

Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Molekulargewicht:

Observed_MW: 68kDa

Calculated_MW: 66kDa

Gen-ID: 6401

UniProt: P16581

Pathways: Thromboxane A2 Receptor Signaling