PMS1 Antikörper

Produktnummer ABIN6569165

Produktdetails anti-PMS1 Antikörper

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PMS1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PMS1

Target: PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))

Andere Bezeichnung: PMS1 (PMS1 Produkte)

Hintergrund:

Synonyms: DNA mismatch repair protein PMS1,FLJ98259,HNPCC3,hPMS1,Human homolog of yeast mutL,Mismatch repair gene PMSL1,pms1,PMS1 postmeiotic segregation increased 1 (S. cerevisiae),PMS1 postmeiotic segregation increased 1,PMS1 protein homolog 1,PMS1,PMSL1,Rhabdomyosarcoma antigen MU RMS 40.10B,Rhabdomyosarcoma antigen MU RMS 40.10E

Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Molekulargewicht:

Observed_MW: 65kDa

Calculated_MW: 62kDa/86kDa/101kDa/105kDa

Gen-ID: 5378

UniProt: P54277