Claudin 7 Antikörper

Produktnummer ABIN5963228

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Claudin 7 in WB. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Claudin 7 Antikörper (ABIN5963228)

Target: Claudin 7 (CLDN7)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Claudin 7 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CLDN7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: Claudin 7

Hintergrund:

Synonyms: CEPTR L2,CEPTRL 2,CEPTRL2,Claudin 1,Claudin 9,Claudin-7,Claudin1,Claudin7,Claudin9,CLD7,CLDN 7,CLDN-7,CLDN7,Clostridium perfringens enterotoxin receptor like 2,CPETR L2,CPETRL 2,CPETRL2,Hs.84359

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.

Molekulargewicht:

Observed_MW: 29kDa

Calculated_MW: 16kDa/22kDa

Gen-ID: 1366

UniProt: O95471

Pathways: Hepatitis C