BMPR1B Antikörper (Bone Morphogenetic Protein Receptor, Type IB)

Details for Product anti-BMPR1B Antibody No. ABIN6569041
Target
Reaktivität
Human, Maus, Ratte
137
46
20
1
1
1
1
1
1
Wirt
Kaninchen
122
15
Klonalität
Polyklonal
Konjugat
Dieser BMPR1B Antikörper ist unkonjugiert
13
12
12
12
12
10
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
113
92
43
13
11
5
3
3
2
2
2
2
2
1
Optionen
Immunogen Recombinant protein of human BMPR1B
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung BMPR1B (BMPR1B Antibody Abstract)
Hintergrund

Synonyms: Activin receptor like kinase 6,Acvrlk6,ALK 6,ALK6,alk6tr,BMP type-1B receptor,BMPR IB,BMPR-1B,Bmpr1b,BMPRIB,BMR1B,Bone morphogenetic protein receptor type 1B,Bone morphogenetic protein receptor type IB,Bone morphogenetic protein receptor type-1B,BR 1b,BR1b,CDw 293,CDw293,CDw293 antigen,CFK 43a,CFK43a,Serine/threonine receptor kinase,zALK 6,zALK6

Background: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 55kDa

Calculated_MW: 56kDa/60kDa

Gen-ID 658
UniProt O00238
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) antibody (ABIN6569041) Western blot analysis of extracts of various cell lines, using BMPR1B Antibody.
Image no. 2 for anti-Bone Morphogenetic Protein Receptor, Type IB (BMPR1B) antibody (ABIN6569041) Immunohistochemistry of paraffin-embedded mouse Intestine using BMPR1B antibody.