BMPR1B Antikörper
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- Target Alle BMPR1B Antikörper anzeigen
- BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BMPR1B Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human BMPR1B (NP_001194.1).
- Isotyp
- IgG
- Top Product
- Discover our top product BMPR1B Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:200 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
- Andere Bezeichnung
- BMPR1B (BMPR1B Produkte)
- Hintergrund
- This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: 55kDa
Calculated_MW: 56kDa/60kDa
- Gen-ID
- 658
- UniProt
- O00238
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