ACVR2A Antikörper

Produktnummer ABIN5964534

Der Kaninchen Polyklonal Anti-ACVR2A-Antikörper wurde für IHC und IF validiert. Er ist geeignet, ACVR2A in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ACVR2A Antikörper (ABIN5964534)

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR2A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ACVR2A Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ACVR2A (NP_001607.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Andere Bezeichnung: ACVR2A

Hintergrund: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Molekulargewicht:

Observed_MW: 58kDa

Calculated_MW: 45kDa/57kDa

Gen-ID: 92

UniProt: P27037