Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) Antikörper

Details zu Produkt Nr. ABIN6568922
Target
Reaktivität
Human, Maus
22
5
5
1
1
1
1
1
1
1
Wirt
Kaninchen
20
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
16
5
5
4
2
1
1
Optionen
Immunogen Recombinant protein of human HSD3B2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung HSD3B2 (HSD3B2 Antibody Abstract)
Hintergrund

Synonyms: Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 2,3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II,Short Chain Dehydrogenase/Reductase Family 11E, Member 2,3-Beta-HSD Adrenal And Gonadal Type,3-Beta-HSD II,3 Beta-Hydroxysteroid Dehydrogenase Type II, Delta 5-Delta 4-Isomerase Type II, 3 Beta-HSD Type II,3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2,3-Beta-Hydroxy-Delta(5)-Steroid Dehydrogenase,3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase.

Background: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht

Observed_MW: 47kDa

Calculated_MW: 24kDa/42kDa

Gen-ID 3284
UniProt P26439
Pathways Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2) antibody (ABIN6568922) Western blot analysis of extracts of various cell lines, using HSD3B2 antibody.