EIF6 Antikörper (Eukaryotic Translation Initiation Factor 6)

Details for Product anti-EIF6 Antibody No. ABIN6568917
Target
Reaktivität
Human
52
39
38
5
4
4
4
4
4
2
2
2
2
1
1
1
1
Wirt
Kaninchen
49
3
1
Klonalität
Polyklonal
Konjugat
Dieser EIF6 Antikörper ist unkonjugiert
4
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
33
13
12
11
10
4
4
3
3
3
2
1
Optionen
Immunogen Recombinant protein of human EIF6
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung EIF6 (EIF6 Antibody Abstract)
Hintergrund

Synonyms: b(2)gcn,B(2)GCN homolog,B4 integrin interactor,Binding protein of beta-4 integrin,CAB,eIF-6,EIF3A,EIF6,Eukaryotic translation initiation factor 3A,Eukaryotic translation initiation factor 6,IF6,ITGB4BP,OK/SW-cl.27,p27 beta 4 integrin binding protein,p27(BBP),p27BBP,RP4-614O4.1

Background: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 27kDa

Calculated_MW: 23kDa/26kDa

Gen-ID 3692
UniProt P56537
Pathways Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Eukaryotic Translation Initiation Factor 6 (EIF6) antibody (ABIN6568917) Western blot analysis of extracts of various cell lines, using EIF6 antibody.
Image no. 2 for anti-Eukaryotic Translation Initiation Factor 6 (EIF6) antibody (ABIN6568917) Immunofluorescence analysis of MCF-7 cells using EIF6 antibody.