Vasopressin Antikörper (Arginine Vasopressin)

Details for Product anti-AVP Antibody No. ABIN6568864
Target
Reaktivität
Human, Maus, Ratte
70
15
10
3
2
1
1
1
Wirt
Kaninchen
70
10
Klonalität
Polyklonal
Konjugat
Dieser Vasopressin Antikörper ist unkonjugiert
12
5
5
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
38
38
25
21
13
12
9
7
2
2
1
1
1
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human AVP
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung AVP (AVP Antibody Abstract)
Hintergrund

Synonyms: ADH,Antidiuretic hormone,Arginine vasopressin neurophysin II,ARVP,AVP,AVP NPII,copeptin,Vasopressin neurophysin II copeptin,VP

Background: This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing  pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). This gene is present in a gene cluster with the related gene oxytocin on chromosome 20.

Molekulargewicht

Observed_MW: 17kDa

Calculated_MW: 17kDa

Gen-ID 551
UniProt P01185
Pathways cAMP Metabolic Process
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Arginine Vasopressin (AVP) antibody (ABIN6568864) Western blot analysis of extracts of various cell lines, using AVP antibody.