Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) Antikörper

Details zu Produkt Nr. ABIN6568775
Target
Reaktivität
Human, Maus
115
66
47
8
6
6
5
3
3
2
2
2
1
1
Wirt
Kaninchen
95
31
15
13
1
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
20
19
10
5
5
3
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
80
50
45
19
18
15
14
14
13
8
7
6
5
4
3
3
3
1
1
1
1
Optionen
Immunogen Recombinant protein of human SERPINC1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SERPINC1 (SERPINC1 Antibody Abstract)
Hintergrund

Synonyms: ANT3,Antithrombin,Antithrombin III,Antithrombin-III,AntithrombinIII,AT 3,AT III,AT3,AT3D,ATIII,Heparin cofactor I,MGC22579,Serine (or cysteine) proteinase inhibitor clade C (antithrombin) member 1,Serine cysteine proteinase inhibitor clade C member 1,Serine proteinase inhibitor clade C member 1,Serpin C1,Serpin family C member 1,Serpin peptidase inhibitor clade C (antithrombin) member 1,SERPINC1,THPH7

Background: The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Molekulargewicht

Observed_MW: 50kDa

Calculated_MW: 52kDa

Gen-ID 462
UniProt P01008
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) antibody (ABIN6568775) Western blot analysis of extracts of various cell lines, using SERPINC1 antibody.
Image no. 2 for anti-Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) antibody (ABIN6568775) Immunofluorescence analysis of U2OS cells using SERPINC1 antibody.