Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) Antikörper

Details zu Produkt Nr. ABIN6568759
Target
Reaktivität
Human, Maus, Ratte
17
8
1
1
1
Wirt
Kaninchen
22
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
20
16
15
3
2
1
Optionen
Immunogen A synthetic peptide of human Lrwd1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung Lrwd1 (LRWD1 Antibody Abstract)
Hintergrund

Synonyms: 1200011O22Rik,AU042569,AW548074,DKFZp434K1815,Leucine rich repeats and WD repeat domain containing 1,Leucine-rich repeat and WD repeat-containing protein 1,LRWD1,LRWD1,ORC-associated protein,ORCA,Origin recognition complex-associated protein

Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 65kDa

Calculated_MW: 70kDa

Gen-ID 222229
UniProt Q9UFC0
Pathways Chromatin Binding
Applikations-hinweise WB 1:200 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) antibody (ABIN6568759) Western blot analysis of extracts of various cell lines, using Lrwd1 antibody.