Dopamine Receptor D3 (DRD3) Antikörper

Details zu Produkt Nr. ABIN6568755
Target
Reaktivität
Human, Maus, Ratte
54
31
28
5
3
3
3
2
2
1
1
1
1
Wirt
Kaninchen
54
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
32
21
15
15
14
13
5
3
3
1
1
Optionen
Immunogen Recombinant protein of human DRD3
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung DRD3 (DRD3 Antibody Abstract)
Hintergrund

Synonyms: 3dopamine receptor,D,D(3) dopamine receptor,Dopamine D3 receptor,Dopamine receptor D3,DRD3,DRD3,ETM1,FET1

Background: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Molekulargewicht

Observed_MW: 44kDa

Calculated_MW: 40kDa/44kDa

Gen-ID 1814
UniProt P35462
Pathways Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Dopamine Receptor D3 (DRD3) antibody (ABIN6568755) Immunofluorescence analysis of U2OS cells using DRD3 antibody.