RASD1 Antikörper

Produktnummer ABIN6568710

Dieses Anti-RASD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RASD1 in WB. Geeignet für Maus und Human.

Kurzübersicht für RASD1 Antikörper (ABIN6568710)

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RASD1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human RASD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Andere Bezeichnung: RASD1

Hintergrund:

Synonyms: Activator of G protein signaling 1,Activator of G protein signaling,Activator of G-protein signaling 1,AGS 1,AGS1,Dexamethasone induced ras related protein 1,Dexamethasone-induced ras protein 1,Dexamethasone-induced Ras-related protein 1,Dexras 1,MGC:26290,RAS dexamethasone induced 1,Ras protein, Dexamethasone-induced, 1,Ras related protein,RASD 1,Rasd1,RASD1

Background: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 31kDa

Calculated_MW: 13kDa/31kDa

Gen-ID: 51655

UniProt: Q9Y272