Ubiquilin 1 Antikörper

Produktnummer ABIN6568702

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Ubiquilin 1 in WB. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für Ubiquilin 1 Antikörper (ABIN6568702)

Target: Ubiquilin 1 (UBQLN1)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ubiquilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Ubiquilin 1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human UBQLN1 (NP_038466.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Ubiquilin 1

Target: Ubiquilin 1 (UBQLN1)

Andere Bezeichnung: UBQLN1

Hintergrund: UBQLN1,DA41,DSK2,PLIC-1,UBQN,XDRP1,This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 70kDa

Calculated_MW: 18kDa/43kDa/59kDa/62kDa

Gen-ID: 29979

UniProt: Q9UMX0