Myoferlin (MYOF) Antikörper

Details zu Produkt Nr. ABIN6568697
Target
Reaktivität
Human, Maus
11
5
2
1
1
1
1
1
1
Wirt
Kaninchen
6
5
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
11
6
5
2
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human MYOF
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung MYOF (MYOF Antibody Abstract)
Hintergrund

Synonyms: Fer 1 like 3, myoferlin (C. elegans) ,Fer 1 like family member 3,Fer 1 like protein 3,Fer-1-like protein 3,FER1L3,myoF,MYOF,Myoferlin

Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Molekulargewicht

Observed_MW: 250kDa

Calculated_MW: 17kDa/46kDa/49kDa/179kDa/229kDa/233kDa/234kDa

Gen-ID 26509
UniProt Q9NZM1
Applikations-hinweise WB 1:200 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Myoferlin (MYOF) antibody (ABIN6568697) Western blot analysis of extracts of various cell lines, using MYOF antibody.