PRMT5 Antikörper (Protein Arginine Methyltransferase 5)

Details for Product anti-PRMT5 Antibody No. ABIN6568604
Target
Reaktivität
Human, Affe, Maus, Ratte
106
43
37
8
6
6
5
3
3
2
2
2
2
Wirt
Kaninchen
93
8
6
Klonalität
Polyklonal
Konjugat
Dieser PRMT5 Antikörper ist unkonjugiert
9
7
7
5
5
5
3
2
2
2
2
2
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
79
52
44
14
13
8
5
3
3
2
2
1
1
1
Optionen
Immunogen A synthetic peptide of human PRMT5
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PRMT5 (PRMT5 Antibody Abstract)
Hintergrund

Synonyms: 72 kDa ICln binding protein,72 kDa ICln-binding protein,ANM5,Histone synthetic lethal 7,S. cerevisiae,homolog of,Histone-arginine N-methyltransferase PRMT5,HMT1 hnRNP methyltransferase like 5,HOMOLOG OF,SKB1,HRMT1L5,IBP72,Jak-binding protein 1,JBP 1,JBP1,PRMT 5,PRMT5,Protein arginine methyltransferase 5,Protein arginine N methyltransferase 5,Protein arginine N methyltransferase 5 N terminally processed,Protein arginine N-methyltransferase 5,S. POMBE,S. POMBE HOMOLOG OF,SKB1,SHK1 KINASE BINDING PROTEIN 1,Shk1 kinase binding protein 1 homolog,Shk1 kinase-binding protein 1 homolog,Shk1 kinase/binding protein 1,S. pombe,homolog of,SKB 1,SKB1,SKB1 homolog,SKB1: SKB1 homolog (S. pombe),SKB1Hs

Background: This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht

Observed_MW: 70kDa

Calculated_MW: 53kDa/66kDa/67kDa/71kDa/72kDa

Gen-ID 10419
UniProt O14744
Pathways Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Protein Arginine Methyltransferase 5 (PRMT5) antibody (ABIN6568604) Immunofluorescence analysis of U2OS cells using PRMT5 antibody.
Image no. 2 for anti-Protein Arginine Methyltransferase 5 (PRMT5) antibody (ABIN6568604) Immunohistochemistry of paraffin-embedded rat brain using PRMT5 antibody.
Image no. 3 for anti-Protein Arginine Methyltransferase 5 (PRMT5) antibody (ABIN6568604) Immunohistochemistry of paraffin-embedded human colon using PRMT5 antibody.
Image no. 4 for anti-Protein Arginine Methyltransferase 5 (PRMT5) antibody (ABIN6568604) Western blot analysis of extracts of various cell lines, using PRMT5 antibody.