EBP Antikörper (Emopamil Binding Protein (Sterol Isomerase))

Details for Product anti-EBP Antibody No. ABIN6568497
Target
Reaktivität
Maus, Ratte
40
11
3
2
1
1
1
1
1
Wirt
Kaninchen
40
Klonalität
Polyklonal
Konjugat
Dieser EBP Antikörper ist unkonjugiert
5
5
5
4
4
4
Applikation
Western Blotting (WB)
35
34
4
2
1
1
1
Optionen
Immunogen A synthetic peptide of human EBP
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung EBP (EBP Antibody Abstract)
Hintergrund

Synonyms: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase,CDPX2 ,CHO2,Cholestenol Delta-isomerase,CPX,CPXD,D8-D7 sterol isomerase,Delta(8)-Delta(7) sterol isomerase,ebp,EBP,Emopamil-binding protein,Msi

Background: The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).

Molekulargewicht

Observed_MW: 26kDa

Calculated_MW: 26kDa

Gen-ID 10682
UniProt Q15125
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) antibody (ABIN6568497) Western blot analysis of extracts of various cell lines, using EBP antibody.