Killer Cell Lectin-Like Receptor Subfamily C, Member 4 (KLRC4) Antikörper

Details zu Produkt Nr. ABIN6568480
Target
Reaktivität
Human, Maus, Ratte
7
Wirt
Kaninchen
4
3
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
7
3
Optionen
Immunogen Recombinant protein of human KLRC4
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung KLRC4 (KLRC4 Antibody Abstract)
Hintergrund

Synonyms: killer cell lectin-like receptor subfamily C, member 4,KLRC4,NK cell receptor F,NKG2 F,NKG2-F type II integral membrane protein,NKG2-F-activating NK receptor,NKG2F,NKG2F

Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member.

Molekulargewicht

Observed_MW: 14kDa

Calculated_MW: 18kDa

Gen-ID 8302
UniProt O43908
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Killer Cell Lectin-Like Receptor Subfamily C, Member 4 (KLRC4) antibody (ABIN6568480) Western blot analysis of extracts of various cell lines, using KLRC4 antibody.