Synonyms: hSMAD6,MAD homolog 6,MADH6,MADH7,Mothers against decapentaplegic homolog 6,Mothers against DPP homolog 6,SMAD 6,SMAD family member 6,SMAD mothers against DPP homolog 6,Smad6,SMAD6
Background: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.