CYP2B6 Antikörper (Cytochrome P450, Family 2, Subfamily B, Polypeptide 6)

Details for Product anti-CYP2B6 Antibody No. ABIN6568418
Target
Reaktivität
Human, Maus, Ratte
52
5
4
2
1
1
1
1
1
Wirt
Kaninchen
49
3
1
Klonalität
Polyklonal
Konjugat
Dieser CYP2B6 Antikörper ist unkonjugiert
4
3
3
2
2
2
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
43
29
29
25
9
4
3
1
1
1
1
Optionen
Immunogen Recombinant protein of human CYP2B6
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung CYP2B6 (CYP2B6 Antibody Abstract)
Hintergrund

Synonyms: 1,4 cineole 2 exo monooxygenase,11B1,CP2B6,CPB 6,CPB6,CYP 2B6,CYP IIB6,CYP2B,CYP2B6,CYP2B7,CYP2B7P,CYPIIB6,Cytochrome P450 2B6,Cytochrome P450 family 2 subfamily B,Cytochrome P450 family 2 subfamily B polypeptide 6,Cytochrome P450 IIB1,Cytochrome P450 phenobarbital inducible,Cytochrome P450 subfamily IIB (phenobarbital inducible),Cytochrome P450 subfamily IIB (phenobarbital inducible) polypeptide 6,Cytochrome P450 subfamily IIB polypeptide 6,EFVM,IIB1,P450,P450 IIB1,P450IIB1

Background: This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described, however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Molekulargewicht

Observed_MW: 66kDa

Calculated_MW: 33kDa/56kDa

Gen-ID 1555
UniProt P20813
Applikations-hinweise WB 1:500 - 1:1000 IHC 1:50 - 1:100
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) antibody (ABIN6568418) Immunohistochemistry of paraffin-embedded human lung using CYP2B6 antibody.
Image no. 2 for anti-Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) antibody (ABIN6568418) Immunohistochemistry of paraffin-embedded mouse lung using CYP2B6 antibody.
Image no. 3 for anti-Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) antibody (ABIN6568418) Western blot analysis of extracts of various cell lines, using CYP2B6 antibody.