HMGCS2 Antikörper (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial))

Details for Product anti-HMGCS2 Antibody No. ABIN6568309
Target
Reaktivität
Human, Maus, Ratte
31
10
9
6
4
4
3
3
2
1
Wirt
Kaninchen
28
3
1
Klonalität
Polyklonal
Konjugat
Dieser HMGCS2 Antikörper ist unkonjugiert
2
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
24
11
8
4
2
1
1
1
Optionen
Immunogen Recombinant protein of human HMGCS2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung HMGCS2 (HMGCS2 Antibody Abstract)
Hintergrund

Synonyms: 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial),3 hydroxy 3 methylglutaryl Coenzyme A synthase 2,3 hydroxy 3 methylglutaryl coenzyme A synthase,3-hydroxy-3-methylglutaryl coenzyme A synthase,HMCS2,HMG CoA synthase,HMG-CoA synthase,HMGCS 2,HMGCS2,Hydroxymethylglutaryl CoA synthase,Hydroxymethylglutaryl CoA synthase mitochondrial,Hydroxymethylglutaryl-CoA synthase,mitochondrial

Background: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 50kDa

Calculated_MW: 50kDa/52kDa/56kDa

Gen-ID 3158
UniProt P54868
Pathways Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2) antibody (ABIN6568309) Western blot analysis of extracts of various cell lines, using HMGCS2 antibody.