HMGCS2 Antikörper (C-Term)

Produktnummer ABIN390764

Produktdetails anti-HMGCS2 Antikörper

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Bindungsspezifität: AA 478-508, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGCS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.

Klon: RB19373

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-HMGCS2 Antikörper (ABIN390764)

Huang, Li, Wang, Zhang, Yan, Li, Xing, Wu, Hu, Jia, Lin, Dang, Song, Gao, Zhang: "Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress." in: Cell research, Vol. 26, Issue 10, pp. 1112-1130, (2017) (PubMed).

Details zu HMGCS2

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Andere Bezeichnung: HMGCS2 (HMGCS2 Produkte)

Synonyme: 1300002P16 antikoerper, mHS antikoerper, DDBDRAFT_0219349 antikoerper, DDBDRAFT_0219924 antikoerper, DDB_0219349 antikoerper, DDB_0219924 antikoerper, Hmgcs1 antikoerper, Mt3h3mg antikoerper, hmgCoA antikoerper, 3-hydroxy-3-methylglutaryl-CoA synthase 2 antikoerper, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 antikoerper, hydroxymethylglutaryl-CoA synthase antikoerper, hydroxymethylglutaryl-coa synthase antikoerper, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 antikoerper, HMGCS2 antikoerper, Hmgcs2 antikoerper, mvaS antikoerper, CNC05080 antikoerper, HMCS1 antikoerper, hgsA antikoerper, MFER_RS00425 antikoerper, LOC100285783 antikoerper, ECU10_0510 antikoerper, Eint_100450 antikoerper

Hintergrund: HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.

Molekulargewicht: 56635

Gen-ID: 3158

NCBI Accession: NP_001159579, NP_005509

UniProt: P54868

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha