HMGCS2 Antikörper (C-Term)
Kurzübersicht für HMGCS2 Antikörper (C-Term) (ABIN390764)
Target
Alle HMGCS2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 478-508, C-Term
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This HMGCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-508 amino acids from the C-terminal region of human HMGCS2.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress." in: Cell research, Vol. 26, Issue 10, pp. 1112-1130, (2017) (PubMed).
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- HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))
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Andere Bezeichnung
- HMGCS2
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Hintergrund
- HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.
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Molekulargewicht
- 56635
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Gen-ID
- 3158
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NCBI Accession
- NP_001159579, NP_005509
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UniProt
- P54868
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Pathways
- Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha
Target
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