Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1) Antikörper

Details zu Produkt Nr. ABIN6568253
Target
Reaktivität
Maus
27
1
Wirt
Kaninchen
25
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
27
19
18
16
4
2
1
1
Optionen
Immunogen Recombinant protein of human PLOD1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PLOD1 (PLOD1 Antibody Abstract)
Hintergrund

Synonyms: 2-oxoglutarate 5-dioxygenase 1,EDS6,LH,LH1,LLH,Lysine hydroxylase,Lysyl hydroxylase 1,PLOD,Plod1,PLOD1,Procollagen lysine 1 2 oxoglutarate 5 dioxygenase 1,Procollagen lysine 2 oxoglutarate 5 dioxygenase 1,Procollagen-lysine

Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: Refer to figures

Calculated_MW: 83kDa/88kDa

Gen-ID 5351
UniProt Q02809
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1) antibody (ABIN6568253) Western blot analysis of extracts of mouse heart, using PLOD1 antibody.