PLOD1 Antikörper
Kurzübersicht für PLOD1 Antikörper (ABIN6568253)
Target
Alle PLOD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human PLOD1
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
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Andere Bezeichnung
- PLOD1
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Hintergrund
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Synonyms: 2-oxoglutarate 5-dioxygenase 1,EDS6,LH,LH1,LLH,Lysine hydroxylase,Lysyl hydroxylase 1,PLOD,Plod1,PLOD1,Procollagen lysine 1 2 oxoglutarate 5 dioxygenase 1,Procollagen lysine 2 oxoglutarate 5 dioxygenase 1,Procollagen-lysine
Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
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Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 83kDa/88kDa
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Gen-ID
- 5351
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UniProt
- Q02809
Target
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