Synonyms: DKFZp686C10199,EC 188.8.131.52,GalNAc T3,GalNAc transferase 3,GalNAc-T3,GalNAcT3,GALNT3,GALT3,HFTC,HHS,MGC61909,OTTHUMP00000204915,OTTHUMP00000204919,Polypeptide GalNAc transferase 3,Polypeptide GalNAc transferase T3,Polypeptide N acetylgalactosaminyltransferase 3,Polypeptide N-acetylgalactosaminyltransferase 3,pp-GaNTase 3,ppGaNTase 3,Protein UDP acetylgalactosaminyltransferase 3,Protein-UDP acetylgalactosaminyltransferase 3,RP23-306G16.2,UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 3,UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 3 (GalNAc T3),UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
Background: This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities.