Asialoglycoprotein Receptor 2 Antikörper

Produktnummer ABIN6568218

Produktdetails anti-Asialoglycoprotein Receptor 2 Antikörper

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Asialoglycoprotein Receptor 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ASGR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Andere Bezeichnung: ASGR2 (ASGR2 Produkte)

Hintergrund:

Synonyms: ASGP R,ASGP-R 2,ASGPR 2,ASGPR2,Asgr2,ASGR2,Asialoglycoprotein receptor 2,C type lectin domain family 4 member H2,C-type lectin domain family 4 member H2,CLEC4H2,HBxAg-binding protein,HBXBP,Hepatic lectin 2,Hepatic lectin H2,Hepatic lectin R2/3,HL-2,Hs.1259,L H2,LH2 ,MGC108546,MHL 2 ,RHL2

Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht:

Observed_MW: 38kDa

Calculated_MW: 32kDa/35kDa

Gen-ID: 433

UniProt: P07307

Pathways: Thyroid Hormone Synthesis