MDFI Antikörper (MyoD Family Inhibitor)

Details for Product anti-MDFI Antibody No. ABIN6568138
Target
Reaktivität
Maus, Ratte
44
8
6
1
1
1
1
1
Wirt
Kaninchen
32
8
4
Klonalität
Polyklonal
Konjugat
Dieser MDFI Antikörper ist unkonjugiert
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
18
15
13
5
4
2
1
1
Optionen
Immunogen Recombinant protein of human MDFI
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung MDFI (MDFI Antibody Abstract)
Hintergrund

Synonyms: I MF,I mfa,Inhibitor of MyoD family a,Mdfi,MDFI,MyoD family inhibitor,Myogenic repressor I-mf,OTTHUMP00000016375,OTTHUMP00000016376,OTTHUMP00000196103,OTTHUMP00000196414,OTTHUMP00000196415

Background: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Molekulargewicht

Observed_MW: 35kDa

Calculated_MW: 25kDa

Gen-ID 4188
UniProt Q99750
Pathways Maintenance of Protein Location
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-MyoD Family Inhibitor (MDFI) antibody (ABIN6568138) Western blot analysis of extracts of various cell lines, using MDFI antibody.