CD38 Antikörper

Details for Product anti-CD38 Antibody No. ABIN6568082
Target
Reaktivität
Human, Maus, Ratte
185
76
21
5
3
1
1
1
Wirt
Kaninchen
116
85
40
7
1
Klonalität
Polyklonal
Konjugat
Dieser CD38 Antikörper ist unkonjugiert
20
16
14
12
6
6
5
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
167
66
57
48
38
34
34
26
23
8
4
3
3
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human CD38
Isotyp IgG
Reinigung Affinity purification
Target
Hintergrund

Synonyms: Acute lymphoblastic leukemia cells antigen CD38,ADP ribosyl cyclase 1,ADP ribosyl cyclase,ADP ribosyl cyclase/cyclic ADP-ribose hydrolase,ADP-ribosyl cyclase 1,ADPRC 1,ADPRC1,cADPr hydrolase 1,CD 38,CD38,CD38 antigen (p45),CD38 antigen,CD38 Molecule,Cd38-rs1,CD38,CD38H,Cyclic ADP ribose hydrolase,Cyclic ADP ribose hydrolase 1,Cyclic ADP-ribose hydrolase 1,EC 3.2.2.5,Ecto nicotinamide adenine dinucleotide glycohydrolase,I-19,I19 (mouse),Lymphocyte differentiation antigen CD38,NAD(+) nucleosidase,NIM-R5 antigen,NIMR5 antigen (mouse),OTTHUMP00000158633,OTTHUMP00000217743,p45,T10

Background: The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 45kDa

Calculated_MW: 13kDa/34kDa

Gen-ID 952
UniProt P28907
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-CD38 antibody (ABIN6568082) Western blot analysis of extracts of Raji cells, using CD38 Antibody.