ARIP4 Antikörper

Produktnummer ABIN6568064

Der Kaninchen Polyklonal Anti-ARIP4-Antikörper wurde für IF validiert. Er ist geeignet, ARIP4 in Proben von Human zu detektieren.

Kurzübersicht für ARIP4 Antikörper (ABIN6568064)

Target: ARIP4 (RAD54L2) (RAD54-Like 2 (RAD54L2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARIP4 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-ARIP4 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human RAD54L2 (NP_055921.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ARIP4

Target: ARIP4 (RAD54L2) (RAD54-Like 2 (RAD54L2))

Andere Bezeichnung: RAD54L2

Hintergrund: Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.

Molekulargewicht:

Calculated_MW: 162kDa

Gen-ID: 23132

UniProt: Q9Y4B4