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Hintergrund
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Synonyms: A15,CCG B7,CD231,CD231 antigen,Cell surface glycoprotein A15,DXS1692E,Membrane component chromosome X surface marker 1,Membrane component X chromosome surface marker 1,MRX58,MXS1,T cell acute lymphoblastic leukemia associated antigen 1,T-cell acute lymphoblastic leukemia-associated antigen 1,TALLA 1,TALLA-1,Tetraspanin 7,Tetraspanin-7,TM4SF2b,Transmembrane 4 superfamily 2b,Transmembrane 4 superfamily member 2,Transmembrane protein A15,TSN7,Tspan 7,Tspan-7,TSPAN7 Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.
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