TRIM21 Antikörper

Produktnummer ABIN6568036

Produktdetails anti-TRIM21 Antikörper

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM21 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human TRIM21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50 - 1:200 IF 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TRIM21

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Andere Bezeichnung: TRIM21 (TRIM21 Produkte)

Synonyme: RNF81 antikoerper, RO52 antikoerper, SSA antikoerper, SSA1 antikoerper, Ro52 antikoerper, Ssa1 antikoerper, tripartite motif containing 21 antikoerper, tripartite motif-containing 21 antikoerper, TRIM21 antikoerper, Trim21 antikoerper

Hintergrund:

Synonyms: 52 kDa ribonucleoprotein autoantigen Ro/SS-A,52 kDa Ro protein,52kD Ro/SSA autoantigen,Autoantigen Ro/SSA,52-KD,E3 ubiquitin-protein ligase TRIM21,RING finger protein 81,RNF81,Ro 52,Ro(SS-A),Ro52,RO52,Sicca syndrome antigen A,Sjoegren syndrome type A antigen,Sjogren syndrome antigen A1,Sjogren syndrome type A antigen,SS-A,SSA,SSA1: Sjogren syndrome antigen A1 (52  kDa ribonucleoprotein autoantigen SS-A/Ro),TRIM21,Tripartite motif protein TRIM21,Tripartite motif-containing 21,Tripartite motif-containing protein 21

Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 45kDa/54kDa

Gen-ID: 6737

UniProt: P19474