TRIM21 Antikörper (Tripartite Motif Containing 21)

Details for Product anti-TRIM21 Antibody No. ABIN6568036
Target
Reaktivität
Human, Maus, Ratte
76
10
8
6
4
3
2
1
1
1
1
Wirt
Kaninchen
62
8
7
3
1
Klonalität
Polyklonal
Konjugat
Dieser TRIM21 Antikörper ist unkonjugiert
6
5
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC)
48
30
20
14
13
11
7
6
6
4
3
2
2
1
1
1
Optionen
Immunogen Recombinant protein of human TRIM21
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TRIM21 (TRIM21 Antibody Abstract)
Hintergrund

Synonyms: 52 kDa ribonucleoprotein autoantigen Ro/SS-A,52 kDa Ro protein,52kD Ro/SSA autoantigen,Autoantigen Ro/SSA,52-KD,E3 ubiquitin-protein ligase TRIM21,RING finger protein 81,RNF81,Ro 52,Ro(SS-A),Ro52,RO52,Sicca syndrome antigen A,Sjoegren syndrome type A antigen,Sjogren syndrome antigen A1,Sjogren syndrome type A antigen,SS-A,SSA,SSA1: Sjogren syndrome antigen A1 (52  kDa ribonucleoprotein autoantigen SS-A/Ro),TRIM21,Tripartite motif protein TRIM21,Tripartite motif-containing 21,Tripartite motif-containing protein 21

Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Molekulargewicht

Observed_MW: Refer to figures

Calculated_MW: 45kDa/54kDa

Gen-ID 6737
UniProt P19474
Applikations-hinweise IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Tripartite Motif Containing 21 (TRIM21) antibody (ABIN6568036) Immunohistochemistry of paraffin-embedded mouse heart using TRIM21 antibody.
Image no. 2 for anti-Tripartite Motif Containing 21 (TRIM21) antibody (ABIN6568036) Immunofluorescence analysis of U2OS cells using TRIM21 antibody.