PSMA4 Antikörper (Proteasome (Prosome, Macropain) Subunit, alpha Type, 4)

Details for Product anti-PSMA4 Antibody No. ABIN6568026
Target
Reaktivität
Human, Affe, Maus, Ratte
53
31
30
4
3
2
2
2
2
2
1
1
1
1
1
Wirt
Kaninchen
35
11
7
Klonalität
Polyklonal
Konjugat
Dieser PSMA4 Antikörper ist unkonjugiert
4
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
30
15
14
13
6
5
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human PSMA4
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PSMA4 (PSMA4 Antibody Abstract)
Hintergrund

Synonyms: HC9 ,HsT17706 ,Macropain subunit C9,MGC111191,MGC12467,MGC24813,Multicatalytic endopeptidase complex subunit C9,Proteasome (prosome macropain) subunit alpha type 4,Proteasome alpha 4 subunit,Proteasome component C9,Proteasome subunit alpha type 4,Proteasome subunit alpha type-4,Proteasome subunit HC9,Proteasome subunit L,PSA4,PSC9 ,PSMA 4,psmA4

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 29kDa

Calculated_MW: 21kDa/29kDa

Gen-ID 5685
UniProt P25789
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 4 (PSMA4) antibody (ABIN6568026) Immunohistochemistry of paraffin-embedded human colon using PSMA4 antibody.
Image no. 2 for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 4 (PSMA4) antibody (ABIN6568026) Western blot analysis of extracts of various cell lines, using PSMA4 antibody.
Image no. 3 for anti-Proteasome (Prosome, Macropain) Subunit, alpha Type, 4 (PSMA4) antibody (ABIN6568026) Immunofluorescence analysis of U2OS cells using PSMA4 antibody.