APEH Antikörper (N-Acylaminoacyl-Peptide Hydrolase)

Details for Product anti-APEH Antibody No. ABIN6567985
Target
Reaktivität
Human, Maus, Ratte
42
28
26
4
4
3
3
3
2
2
1
1
1
Wirt
Kaninchen
42
Klonalität
Polyklonal
Konjugat
Dieser APEH Antikörper ist unkonjugiert
4
3
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
27
13
10
9
5
3
2
2
2
1
Optionen
Immunogen Recombinant protein of human APEH
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung APEH (APEH Antibody Abstract)
Hintergrund

Synonyms: AARE,ACPH,ACPH,Acyl peptide hydrolase,Acyl-peptide hydrolase,Acylamino acid releasing enzyme,Acylamino-acid-releasing enzyme,Acylaminoacyl peptidase,Acylaminoacyl-peptidase,APEH,APH,N acylaminoacyl peptide hydrolase,OPH,Oxidized protein hydrolase

Background: This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

Molekulargewicht

Observed_MW: 80-108kDa

Calculated_MW: 81kDa

Gen-ID 327
UniProt P13798
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-N-Acylaminoacyl-Peptide Hydrolase (APEH) antibody (ABIN6567985) Western blot analysis of extracts of various cell lines, using APEH antibody.
Image no. 2 for anti-N-Acylaminoacyl-Peptide Hydrolase (APEH) antibody (ABIN6567985) Immunofluorescence analysis of HeLa cells using APEH antibody.