MANF Antikörper

Produktnummer ABIN6567918

Der Kaninchen Polyklonal anti-MANF Antikörper (ABIN6567918) detektiert spezifisch MANF in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MANF Antikörper (ABIN6567918)

Target: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MANF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MANF Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human MANF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MANF

Target: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Andere Bezeichnung: MANF

Hintergrund:

Synonyms: Arginine rich mutated in early stage tumors,Arginine rich protein,Arginine-rich protein,ARMET,ARMET protein,ARP,Manf,MANF,Mesencephalic astrocyte derived neurotrophic factor,Mesencephalic astrocyte-derived neurotrophic factor,MGC142148,MGC142150,Protein ARMET

Background: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.

Molekulargewicht:

Observed_MW: 16kDa

Calculated_MW: 20kDa

Gen-ID: 7873

UniProt: P55145