Synonyms: 35 kDa dystrophin associated glycoprotein ,35 kDa dystrophin-associated glycoprotein,35DAG,CMD1L,DAGD,Delta-sarcoglycan,Delta-SG,Dystrophin associated glycoprotein delta sarcoglycan,LGMD2F,MGC22567,Placental delta sarcoglycan,Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) ,SG delta,SGCD,SGCD,SGCDP,SGD
Background: The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.