Rhotekin Antikörper (RTKN)

Details for Product anti-RTKN Antibody No. ABIN6567898
Target
Reaktivität
Human, Maus, Ratte
29
11
10
5
4
3
3
3
2
2
1
1
1
Wirt
Kaninchen
22
8
Klonalität
Polyklonal
Konjugat
Dieser Rhotekin Antikörper ist unkonjugiert
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
24
12
10
8
2
2
1
1
Optionen
Immunogen Recombinant protein of human RTKN
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung RTKN (RTKN Antibody Abstract)
Hintergrund

Synonyms: Rhotekin,Rtkn,RTKN,RTKN1

Background: This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht

Observed_MW: 63kDa

Calculated_MW: 56kDa/61kDa/62kDa

Gen-ID 6242
UniProt Q9BST9
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Rhotekin (RTKN) antibody (ABIN6567898) Immunofluorescence analysis of MCF-7 cells using RTKN antibody.
Image no. 2 for anti-Rhotekin (RTKN) antibody (ABIN6567898) Western blot analysis of extracts of various cell lines, using RTKN antibody.