Synonyms: 12 O tetradecanoylphorbol 13 acetate induced sequence 7,IFRD1,IFRD1,interferon related developmental regulator 1,Interferon-related developmental regulator 1,Nerve growth factor inducible protein PC4,Nerve growth factor-inducible protein PC4,PC4,Pheochromocytoma cell 4,TIS7,TPA induced sequence 7
Background: This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants.