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ETV1 Antikörper

ETV1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6567870
  • Target Alle ETV1 Antikörper anzeigen
    ETV1 (Ets Variant 1 (ETV1))
    Reaktivität
    • 33
    • 33
    • 22
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 44
    • 3
    • 1
    Kaninchen
    Klonalität
    • 46
    • 2
    Polyklonal
    Konjugat
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ETV1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ETV1 (NP_004947.2).
    Isotyp
    IgG
    Top Product
    Discover our top product ETV1 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ETV1 (Ets Variant 1 (ETV1))
    Andere Bezeichnung
    ETV1 (ETV1 Produkte)
    Synonyme
    er81 antikoerper, XER81 antikoerper, MGC75591 antikoerper, ER81 antikoerper, Etsrp81 antikoerper, ETS variant 1 antikoerper, ets variant 1 antikoerper, ETS variant 1 S homeolog antikoerper, etv1 antikoerper, ETV1 antikoerper, Etv1 antikoerper, etv1.S antikoerper
    Hintergrund
    This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
    Molekulargewicht

    Calculated_MW: 43kDa/48kDa/50kDa/52kDa/53kDa/55kDa

    Gen-ID
    2115
    UniProt
    P50549
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