Agouti Signaling Protein (ASIP) Antikörper

Details zu Produkt Nr. ABIN6567853
Target
Reaktivität
Human
29
3
Wirt
Kaninchen
30
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF)
18
12
8
3
2
1
1
Optionen
Immunogen Recombinant protein of human ASIP
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ASIP (ASIP Antibody Abstract)
Hintergrund

Synonyms: agouti signaling protein,Agouti switch protein,AGSW,AGTI,AGTIL,ASIP,ASP,SHEP9

Background: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Molekulargewicht

Calculated_MW: 14kDa

Gen-ID 434
UniProt P42127
Pathways Cell-Cell Junction Organization, Feeding Behaviour
Applikations-hinweise IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Agouti Signaling Protein (ASIP) antibody (ABIN6567853) Immunofluorescence analysis of HeLa cells using ASIP antibody.