HFE Antikörper (Hemochromatosis)

Details for Product anti-HFE Antibody No. ABIN6567776
Target
Reaktivität
Human, Maus
52
21
19
2
2
2
2
1
1
1
1
Wirt
Kaninchen
42
11
Klonalität
Polyklonal
Konjugat
Dieser HFE Antikörper ist unkonjugiert
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
36
19
13
8
7
6
3
2
1
1
1
Optionen
Immunogen Recombinant protein of human HFE
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung HFE (HFE Antibody Abstract)
Hintergrund

Synonyms: dJ221C16.10.1,Hemochromatosis,Hemochromatosis protein,Hereditary hemochromatosis protein,Hereditary hemochromatosis protein HLA H,HFE 1,HFE,HFE,HFE1,HH,High Fe,HLA H,HLA-H,HLAH,MGC:150812,MGC10379,MGC103790,MHC class I like protein HFE,MVCD7,TFQTL2

Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

Molekulargewicht

Observed_MW: 50kDa

Calculated_MW: 8kDa/18kDa/27-40kDa

Gen-ID 3077
UniProt Q30201
Pathways Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Hemochromatosis (HFE) antibody (ABIN6567776) Western blot analysis of extracts of various cell lines, using HFE antibody.
Image no. 2 for anti-Hemochromatosis (HFE) antibody (ABIN6567776) Immunofluorescence analysis of MCF-7 cells using HFE antibody.