Ataxin 3 Antikörper (ATXN3)

Details for Product anti-ATXN3 Antibody No. ABIN6567724
Target
Reaktivität
Human, Maus
65
31
29
5
5
5
4
4
3
3
3
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
62
2
1
Klonalität
Polyklonal
Konjugat
Dieser Ataxin 3 Antikörper ist unkonjugiert
4
4
4
3
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (IF), Western Blotting (WB)
51
32
27
13
8
5
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human ATXN3
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ATXN3 (ATXN3 Antibody Abstract)
Hintergrund

Synonyms: AT3,Ataxin 3,ataxin 3 variant h,ataxin 3 variant m,ataxin 3 variant ref,Ataxin-3,ATX3,ATX3,ATXN3,EC 3.4.22.,JOS,Josephin,Machado Joseph disease (spinocerebellar ataxia 3,olivopontocerebellar ataxia 3,autosomal dominant,ataxin 3),Machado Joseph disease,Machado Joseph disease protein 1,Machado-Joseph disease protein 1,Machado-Joseph disease protein 1 homolog,MJD,MJD gene,MJD1,Olivopontocerebellar ataxia 3,OTTHUMP00000221583,OTTHUMP00000221585,OTTHUMP00000221586,OTTHUMP00000221587,OTTHUMP00000231995,OTTHUMP00000231997,Rsca3,SCA3,SCA3 gene,Spinocerebellar ataxia type 3 protein

Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht

Observed_MW: 50kDa

Calculated_MW: 20kDa/35kDa/39kDa/41kDa

Gen-ID 4287
UniProt P54252
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Ataxin 3 (ATXN3) antibody (ABIN6567724) Western blot analysis of extracts of various cell lines, using ATXN3 antibody.
Image no. 2 for anti-Ataxin 3 (ATXN3) antibody (ABIN6567724) Immunofluorescence analysis of HeLa cells using ATXN3 antibody.