Synonyms: FLJ37460,HUP1,OTTHUMP00000002534,Paired box 7,Paired box gene 7,Paired box homeotic gene 7,Paired box protein Pax-7,Paired domain gene 7,Paired domain gene HuP1,Pax7,PAX7 transcriptional factor,PAX7/FKHR fusion gene,included,PAX7,PAX7B,RGD1564360,RMS2
Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.