BRWD1 Antikörper

Produktnummer ABIN6567606

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BRWD1 in WB. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für BRWD1 Antikörper (ABIN6567606)

Target: BRWD1 (Bromodomain and WD Repeat Domain Containing 1 (BRWD1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRWD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BRWD1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human BRWD1 (NP_001007247.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BRWD1

Target: BRWD1 (Bromodomain and WD Repeat Domain Containing 1 (BRWD1))

Andere Bezeichnung: BRWD1

Hintergrund: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

Molekulargewicht:

Observed_MW: 284kDa

Calculated_MW: 13kDa/248kDa/257kDa/262kDa

Gen-ID: 54014

UniProt: Q9NSI6