Synonyms: 1 phosphatidylinositol 4 phosphate 5 kinase 2 beta,1 phosphatidylinositol 4 phosphate kinase,1-phosphatidylinositol-5-phosphate 4-kinase 2-beta,Diphosphoinositide kinase 2 beta ,Diphosphoinositide kinase 2-beta,diphosphoinositide kinase,EC 220.127.116.11,Phosphatidylinositol 4 phosphate 5 kinase type II beta,phosphatidylinositol 4 phosphate 5 kinase type II beta isoform a,Phosphatidylinositol-5-phosphate 4-kinase type II beta,Phosphatidylinositol-5-phosphate 4-kinase type-2 beta,PI(5)P 4-kinase type II beta,PI42B,PI5P4KB,Pip4k2b,PIP4KII-beta,PIP5K2B,PIP5KII beta,PIP5KIIB,PIP5KIIbeta,PTDINS(4) P 5 kinase,PtdIns(4) P 5-kinase isoform 2 beta,PtdIns(5)P-4-kinase isoform 2-beta
Background: The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.