Synonyms: Adapter-related protein complex 2 sigma subunit,Adaptor protein complex AP 2 subunit sigma,Adaptor protein complex AP-2 subunit sigma,Adaptor protein complex AP2 subunit sigma,Adaptor related protein complex 2 sigma 1 subunit,AI043088,AP 17,AP 2 complex subunit sigma 1,AP-2 complex subunit sigma,AP17,AP17 delta,AP2 complex subunit sigma 1,Ap2s1,AP2S1,CLAPS 2,CLAPS2,Clathrin adaptor complex AP2,sigma subunit,Clathrin adaptor protein AP17,Clathrin assembly protein 2 small chain,Clathrin associated/assembly/adaptor protein small 2,Clathrin associated/assembly/adaptor protein small 2,17-KD,Clathrin associated/assembly/adaptor protein,small 2 (17kD),Clathrin coat assembly protein AP17,Clathrin coat associated protein AP17,Clathrin coat-associated protein AP17,HA2 17 kDa subunit,MGC62945,Plasma membrane adaptor AP 2 17 kDa protein,Plasma membrane adaptor AP-2 17 kDa protein,Plasma membrane adaptor AP2 17 kDa protein,Sigma adaptin 3b,Sigma2 adaptin,Sigma2-adaptin
Background: One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants.