ARHGDIA Antikörper

Produktnummer ABIN6567345

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ARHGDIA in WB und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Affe.

Kurzübersicht für ARHGDIA Antikörper (ABIN6567345)

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Reaktivität: Human, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGDIA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-ARHGDIA Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ARHGDIA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IF 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Andere Bezeichnung: ARHGDIA

Hintergrund:

Synonyms: ARHGDIA,fa96g11,GDIA 1,GDIA1,GDIR1,MGC117248,NPHS8,Rho GDI 1,Rho GDI alpha,Rho GDI,Rho GDP dissociation inhibitor (GDI) alpha,Rho GDP dissociation inhibitor 1,Rho GDP dissociation inhibitor alpha,Rho GDP-dissociation inhibitor 1,Rho-GDI alpha,RhoGDI 1,RhoGDI alpha,RHOGDI,RhoGDI1,wu:fa96g11,zgc:55554,zgc:77681

Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 23kDa

Calculated_MW: 18kDa/23kDa

Gen-ID: 396

UniProt: P52565

Pathways: Neurotrophin Signalübertragung