Cat Antikörper

Details zu Produkt Nr. ABIN6567261
Target
Reaktivität
Human, Maus, Ratte
47
17
7
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Wirt
Kaninchen
37
11
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunoprecipitation (IP), Western Blotting (WB)
40
23
16
7
6
3
2
1
Optionen
Immunogen Recombinant protein of human CAT
Isotyp IgG
Reinigung Affinity purification
Target
Hintergrund

Synonyms: Cas1,CAT,CATA,Catalase,Cs1,MGC138422,MGC138424

Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Molekulargewicht

Observed_MW: 60kDa

Calculated_MW: 59kDa

Gen-ID 847
UniProt P04040
Applikations-hinweise WB 1:1000 - 1:3000 IP 1:20 - 1:50
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Cat antibody (ABIN6567261) Western blot analysis of extracts of various cell lines, using CAT antibody.
Image no. 2 for anti-Cat antibody (ABIN6567261) Immunoprecipitation analysis of 100ug extracts of HepG2 cells using 3ug CAT antibody.