ACTN1 Antikörper (Actinin, alpha 1)

Details for Product anti-ACTN1 Antibody No. ABIN6567190
Target
Reaktivität
Human, Affe, Maus
62
25
21
6
6
5
5
4
4
4
3
2
1
Wirt
Kaninchen
48
13
1
Klonalität
Polyklonal
Konjugat
Dieser ACTN1 Antikörper ist unkonjugiert
4
3
3
3
2
2
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
50
28
24
20
8
7
5
4
4
3
2
1
1
Optionen
Immunogen Recombinant protein of human ACTN1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ACTN1 (ACTN1 Antibody Abstract)
Hintergrund

Synonyms: actinin 1 smooth muscle,Actinin alpha 1,actinin,alpha 1,ACTN 1,Actn1,ACTN1,Alpha Actinin 1,Alpha actinin cytoskeletal isoform,Alpha-actinin cytoskeletal isoform,Alpha-actinin-1,BDPLT15,F actin cross linking protein,F-actin cross-linking protein,FLJ40884,FLJ54432,Non muscle alpha actinin 1,Non-muscle alpha-actinin-1

Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 110kDa

Calculated_MW: 102kDa/103kDa/105kDa/107kDa

Gen-ID 87
UniProt P12814
Pathways Cell-Cell Junction Organization
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Actinin, alpha 1 (ACTN1) antibody (ABIN6567190) Immunohistochemistry of paraffin-embedded human liver cancer using ACTN1 antibody.
Image no. 2 for anti-Actinin, alpha 1 (ACTN1) antibody (ABIN6567190) Western blot analysis of extracts of various cell lines, using ACTN1 antibody.