MTMR3 Antikörper (Myotubularin Related Protein 3)

Details for Product anti-MTMR3 Antibody No. ABIN6567026
Target
Reaktivität
Human
7
1
Wirt
Kaninchen
4
4
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
8
3
1
Optionen
Immunogen Recombinant protein of human MTMR3
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung MTMR3 (MTMR3 Antibody Abstract)
Hintergrund

Synonyms: FYVE domain-containing dual specificity protein phosphatase 1,FYVE-DSP1,MTMR3,MTMR3,Myotubularin-related protein 3,Zinc finger FYVE domain-containing protein 10

Background: This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 150kDa

Calculated_MW: 129kDa/130kDa/133kDa

Gen-ID 8897
UniProt Q13615
Pathways Inositol Metabolic Process
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Myotubularin Related Protein 3 (MTMR3) antibody (ABIN6567026) Western blot analysis of extracts of various cell lines, using MTMR3 antibody.