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MRPS12 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MRPS12 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN6566989

Kurzübersicht für MRPS12 Antikörper (ABIN6566989)

Target

Alle MRPS12 Antikörper anzeigen
MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

Reaktivität

  • 28
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 27
  • 1
Kaninchen

Klonalität

  • 28
Polyklonal

Konjugat

  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MRPS12 Antikörper ist unkonjugiert

Applikation

  • 21
  • 13
  • 10
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Aufreinigung

    Affinity purification

    Immunogen

    Recombinant protein of human MRPS12

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:1000 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))

    Andere Bezeichnung

    MRPS12

    Hintergrund

    Synonyms: 28S ribosomal protein S12,28S ribosomal protein S12 mitochondrial,mitochondrial,Mitochondrial ribosomal protein S12,MRP-S12,MRPS12,MT-RPS12,RPMS12,RPS12,RPSM12,RT12,S12mt

    Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.

    Molekulargewicht

    Observed_MW: 14kDa

    Calculated_MW: 15kDa

    Gen-ID

    6183

    UniProt

    O15235

    Pathways

    Sensory Perception of Sound
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