ABCA4 Antikörper (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4)

Details for Product anti-ABCA4 Antibody No. ABIN6566982
Target
Reaktivität
Human, Maus, Ratte
35
12
7
4
4
2
2
1
1
1
Wirt
Kaninchen
26
8
6
Klonalität
Polyklonal
Konjugat
Dieser ABCA4 Antikörper ist unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
27
17
13
2
2
1
1
1
Optionen
Immunogen Recombinant protein of human ABCA4
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ABCA4 (ABCA4 Antibody Abstract)
Hintergrund

Synonyms: ABC 10,ABC A4,ABC transporter,retinal-specific,ABC10,ABCA 4,abcA4,ABCA4,ABCR,ARMD 2,ARMD2,ATP binding cassette 10,ATP binding cassette sub family A member 4,ATP binding cassette sub family A member4,ATP binding cassette transporter,ATP binding cassette transporter retinal specific,ATP binding cassette,sub family A (ABC1),member 4,ATP binding cassette,sub family A (ABC1),member4,ATP binding cassette10,ATP binding transporter,retina specific,ATP-binding cassette sub-family A member 4,CORD 3,CORD3,DKFZp781N1972,FFM,FLJ17534,Photoreceptor rim protein,Retina specific ABC transporter,Retinal specific ATP binding cassette transporter,Retinal-specific ATP-binding cassette transporter,RIM ABC transporter,RIM protein,RmP,RP 19,RP19,Stargardt disease protein,STGD,STGD1

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Molekulargewicht

Observed_MW: 256kDa

Calculated_MW: 255kDa

Gen-ID 24
UniProt P78363
Applikations-hinweise WB 1:1000 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4) antibody (ABIN6566982) Western blot analysis of extracts of various cell lines, using ABCA4 antibody.